Can I use Mira on HRT?Updated 3 months ago

Yes, you can use Mira while on hormone replacement therapy (HRT), but it’s important to keep in mind how it may affect the data.  No testing modality—whether serum, DUTCH, or Mira—can definitively determine if hormone replacement therapy (HRT) is fully "working".

Instead, Mira provides quantitative data to use alongside clinical context and symptoms. It’s important to note that hormone absorption, type of HRT, and route of administration (oral, transdermal, vaginal, etc.) can all impact hormone levels in urine, which may affect how results are interpreted. If you are still in perimenopause—meaning you're experiencing ongoing natural hormonal fluctuations—Mira can be a valuable tool for monitoring how your hormones shift over time and whether HRT is helping to support more coordinated hormonal patterns. It’s particularly helpful for identifying ovulatory versus anovulatory cycles, tracking estrogen variability, and detecting luteal phase defects, all of which are common during the perimenopausal transition.

We often recommend comparing results before and after starting HRT to observe any shifts in hormone trends. Mira can affirm symptoms and help guide conversations around timing and treatment strategies.

For more details, we recommend reviewing our clinical insights document here: Clinical Insights on Hormonal Monitoring with Mira