Cortisol Wands
New Mira Cortisol Pattern™️Wands
What are Mira Cortisol Pattern™️Wands
A test wand that runs on the existing Mira Monitor. The patient dips the wand in a urine sample, inserts it into the monitor, and results sync to the Mira app in about 16 minutes. Mira measures urinary free cortisol, a biological signal related to st
Does "free cortisol" mean cortisol the body is not using?
No, the reverse. Free cortisol is the active fraction; the protein-bound pool is the reserve. The cortisol found in urine is a small overflow from the active pool, and its quantity reflects how much active cortisol was circulating. The cortisol the b
What exactly does the cortisol wand measure?
It is a fluorescence lateral flow immunoassay designed to measure urinary free cortisol, the same detection approach as the other Mira wands. Free cortisol is the unbound, biologically active fraction of circulating cortisol. Most cortisol in blood i
How do the Mira Cortisol Pattern™️Wands work?
When does the patient test?. We generally suggest testing twice a day: a first-morning sample and an evening sample taken at a consistent interval after waking (roughly 10 to 12 hours). That pairing is what the 30-wand pack is built around, and it is
Is the Cortisol result corrected for urine concentration (creatinine or specific gravity)?
No. A spot sample gives a concentration, not an excretion rate, so the result depends on urine volume as well as on how much cortisol entered the urine. A very dilute sample can read lower than the underlying excretion. Patients are coached to keep f
How is the Mira Cortisol different from serum or a 4-point salivary cortisol?
Serum measures total cortisol (about 90% protein-bound) at a single moment, and is strongly time-of-day dependent. It is the standard sample for a morning cortisol in a suspected adrenal insufficiency workup and for stimulation and suppression testin
How is the Mira Cortisol different from a DUTCH test?
DUTCH measures free cortisol, free cortisone, and cortisol metabolites across four or five timed dried-urine samples by mass spectrometry, creatinine-corrected and reported against population ranges, with an optional saliva add-on for the awakening r
How is the Mira Cortisol different from a 24-hour urinary free cortisol?
A 24-hour collection integrates free cortisol excretion across a full day and is a guideline-endorsed initial test for Cushing syndrome, typically with at least two collections and creatinine measured to check completeness. A Mira wand tests a single
Are there factors other than stress that move urinary free cortisol?
Many. Cortisol is not a stress meter. Non-stress influences include illness and inflammation, pain, alcohol, poorly controlled glucose, sleep disruption and shift work, hydration and urine dilution (no creatinine correction), licorice, and a wide ran
What should the Mira Cortisol Pattern™️ not be used for?
If a patient's presentation warrants cortisol testing, that testing should be ordered regardless of what the Mira pattern shows.